New drug shows promise in reducing diabetes complications

NEW YORK: Scientists at New York University Langone Health have discovered a new drug that reduces the serious effects of diabetes, which could be a ray of hope for millions of patients in the future.

According to the report, in experimental research conducted on mice, this drug, named RAGE406R, was effective in reducing inflammation, limiting cell damage and improving heart and kidney recovery.

The study also revealed that the drug accelerates the healing process of wounds, which is a major problem for diabetic patients.

Experts say that this drug works differently from other diabetes drugs. It focuses on preventing damage inside cells rather than lowering blood sugar levels.

The drug works by blocking the interaction of two harmful proteins, RAGE and DIAPH1, which reduces the harmful effects of advanced glycation end products.

Advanced glycation end products are compounds that form when sugars bind to proteins or fats, and this process increases in sugar. When these compounds bind to the AGE protein, inflammation and cell damage increase, in which DIAPH1 plays an important role.

According to the study, applying the drug to the skin of mice caused wounds to heal faster, which made it clear that the drug could be helpful in treating slow-healing wounds in diabetic patients.

The research has been published in the journal Cell Chemical Biology and, despite being in its early stages, is being seen as a major breakthrough in the treatment of diabetes. If successful in human trials, this drug could bring new hope to patients with type 1 and type 2 diabetes.